J. C. Masdeu

Body mass regulation in humans is associated with dopamine synthesis capacity and dopamine receptor profile measured with positron emission tomography

The presence and rate of weight gain in the 1–2 years prior to scanning was associated with increased presynaptic dopamine synthesis capacity in the ventral striatum and midbrain, important components of the reward network, and data suggest that upregulation of body mass beyond the normal range is related to increased...