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J. C. Santos-Barbosa

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Open access Aug 2026

Antibody Recognition and Functional Activity Against a Conserved Trypanosoma cruzi Peptide and Its Natural Variants in Kinetoplastids

The TcTLE peptide (TLEEFSAKL), located at the amino-terminus of the Trypanosoma cruzi Kinetoplastid Membrane Protein-11 (KMP-11), induces robust humoral and cellular immune responses, suggesting its potential for serological diagnostics or immunoprophylaxis. However, natural variants of this sequence exist in Leishmani...

J. Zuluaga, F. Gúzman, J. C. Santos-Barbosa et al. · 0 citations

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