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J. Chen

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Open access Oct 2026

Transcription factor NFAT1 mediates endothelial-to-mesenchymal transition and atherogenesis under disturbed flow conditions

Atherosclerosis is a prevalent vascular pathology with a partially understood pathogenesis. Notably, lesions manifest non-uniformly, favoring bifurcations and curvatures characterized by complex hemodynamics. We hypothesize that disturbed flow (DF) plays a pivotal role in disease initiation and progression....

J. Chen, Q. Guan · 0 citations

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