Author

Jeroen D. C. Codée

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Open access Aug 2026

Functional Differentiation of GH172 Arabinofuranosidases Through Divergent Quaternary Structures

Mycobacteria synthesise the unusual glycan ᴅ-arabinan as a major component of the cell wall glycoconjugates arabinogalactan (AG) and lipoarabinomannan (LAM). We previously identified Dysgonomonas gadei, a member of the Bacteroidota, as capable of complete ᴅ-arabinan degradation through the concerted action of endo- and...

Jennifer Ross, Moescha J. Hoopman, Florian Küllmer et al. · bioRxiv · 0 citations

Open access Jul 2026

The development of activity-based mannanase probes

β-Mannanases are endo-acting glycoside hydrolases (GHs) that cleave β-1,4 glycosidic linkages in mannan-rich plant cell wall polysaccharides. They find application in the food and paper industries. Activity-based probes (ABPs) are powerful tools for GH profiling in complex biological samples, yet to date, bespoke ABPs...

Massimo Tedeschi, Vincent A. J. Lit, Nicholas G. S. McGregor et al. · Chemical Science · 1 citation