Distinct nigral and brainstem pathology markers map onto separable subthalamic electrophysiological signatures in Parkinson’s disease
Subthalamic local field potentials (LFPs) are increasingly used as physiomarkers of the symptomatic state in Parkinson’s disease, but their relationship to the underlying neurodegenerative pathology remains unclear. Here, we combined OFF-medication subthalamic LFP recordings with quantitative MRI markers of nigral and...