DCAF7 is one of the few DCAFs expressed in hematopoietic stem cells (HSCs). Using a conditional knockout mouse model, we discovered that the absence of DCAF7 leads to accumulation of differentiating progenitors in the bone marrow, and impairs self-renewal capacity of HSCs upon transplantation. Furthermore, loss of Dcaf...
Johanna Melo-Cardenas, Lavanya Bezavada, Te Ling et al.· Nature Communications· 0 citations
Summary Background Human pregnancy presents a unique physiological state that allows for growth of an antigenically dissimilar foetus. The immune system plays a key role in establishing and maintaining successful pregnancy, yet detailed understanding of immunological responses in pregnancy is lacking. Methods We define...
Jennifer R. Habel, Thi H. O. Nguyen, L. Allen et al.· EBioMedicine· 0 citations
MakeMyFigure is introduced, a free and open-source platform for data visualization, analysis, and creation of multi-panel scientific figures that combines accessible, code-free figure creation with panel-level computational reproducibility.
Suresh Poudel, Him K. Shrestha, J. Crawford et al.· bioRxiv· 0 citations
A subset of CMV-positive individuals with a marked expansion of CMV-specific CD8 T cells associated with markers of poor HIV-1 control are observed, which suggests an inappropriately elderly immune tone phenotype with HIV-1-CMV co-infection.
Brandi L. Clark, E. Allen, S. Schattgen et al.· Journal of the Pediatric Inf...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
