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J. Cristante

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Open access Aug 2026

EP1002 - ECE_3406 - Real-world BMI outcomes in adult patients with acquired hypothalamic obesity treated with setmelanotide for up to 9 months in France

Acquired hypothalamic obesity (aHO) arises from physical injury to the hypothalamus caused by trauma, tumours, treatment-related damage, inflammation, or developmental abnormalities, leading to disrupted melanocortin-4 receptor (MC4R) signalling and marked by accelerated, sustained weight gain. In a 52-week place...

P. Faucher, S. Chalopin, Emilie Montastier et al. · 0 citations

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