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Author

J. Currier

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2 papers indexed here

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Open access Aug 2026

Evaluation of inactivated and live attenuated, tetravalent dengue vaccine prime-boost strategies in a randomized, open-label, phase I study: implications for understanding immune correlates of protection

ABSTRACT Vaccines that elicit balanced, protective immunity to all four dengue virus (DENV) types are needed to reduce the global burden of dengue disease. Achieving this goal has been a challenge for dengue vaccine developers, particularly when immunizing dengue immunologically naïve individuals. In this randomized, p...

M. Koren, S. Pollett, Keisha Akerele et al. · 0 citations
Jul 2026

Characterization of Non-Neutralizing Antibody Responses in a Dengue Virus-4 Human Challenge Model 2243013

Primary infection with one of the four dengue viruses (DENV-1—4) induces serotype-specific antibodies (Abs) that confer durable protection and cross-reactive Abs that offer transient immunity. While neutralizing Ab titers are commonly used to assess protection, they do not reliably predict disease outcome, and th...

Y. Zheng, J. Currier, Heather Fribert et al. · 0 citations

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