J. de Oca

Synthesis, DFT studies, and molecular docking of novel pyrazole semicarbazones targeting GPb, PPA-II, and DPP-4 enzymes

Six new phenyl-1 H -pyrazole-carbaldehyde semicarbazone derivatives ( 1 – 6 ) have been synthesized and characterized by FT-IR, NMR ( 1 H and 13 C), and mass spectrometry. NMR analysis indicated that these compounds in DMSO-d 6 exhibit a cisE isomeric form. This evidence is supported by computational...