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J. de Vrij

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Open access Jul 2026

Small-scale bioreactor cultivation of HEK293-based suspension cells increases extracellular vesicle yield

It is demonstrated that Expi293F-derived EV yield can be increased by culturing cells in a scalable bioreactor system, paving the way towards the production of therapeutic-based EVs in a scalable and reproducible manner suitable for future (pre-)clinical applications.

W. Woud, E. Dilla, N. Dits et al. · 0 citations

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