Abstract Background Substance Use Disorders (SUDs) are major contributors to global morbidity and premature mortality. While their adverse physical and psychiatric sequalae are widely attributed to toxic effects of substance exposure, accumulating evidence suggests that inherited liability to addiction also shapes broa...
M. Graczyk, C. Albiñana, A. Lee et al.· International Journal of Neu...· 0 citations
In both AFR and EUR, environmental factors explained most of the variance in AUD criterion count, but polygenic risk was also a statistically significant predictor, and the pattern of results for OUD was similar.
P. Na, J. Deak, D. Levey et al.· International Journal of Neu...· 0 citations
These findings expand the known genetic architecture of migraine across ancestries and provide a genetics-led map connecting association signals with biological pathways, multimorbidity and candidate therapeutic mechanisms, providing a foundation for future functional and translational studies.
C. Overstreet, M. Galimberti, K. Harsan et al.· medRxiv· 0 citations
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