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Open access Jul 2026

Formulation and assessment of long-acting pharmaceutical co-formulated crystals.

Drug crystallization is a fundamental approach to extending release through enhanced solid‑state stability and tunable particle size. Drug-release kinetics can be further modulated through co-crystallization, which alters drug-molecule-to-drug-molecule interactions, and can be used to simultaneously deliver agents with...

Jamie L. Hernandez, Neeti R. Prasad, J. Daniel et al. · 0 citations
Aug 2026

Engineering Lipid Nanoparticles through Integrated Compositional and Ligand Targeting Enhances β Cell-Directed RNA Delivery.

A dual-targeting LNP engineering strategy that integrates high-throughput compositional screening with surface conjugation of β cell-specific targeting ligands to enable selective gene delivery to pancreatic β cells is developed and establishes a versatile platform for RNA therapeutics and gene-editing applications in...

Di Yu, Yining Zhu, A. Roca-Rivada et al. · 1 citation

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