J. Dymek

From retina to brain: retinal dysfunction and dopaminergic neurodegeneration in Drosophila models of Parkinson’s disease

Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons within the substantia nigra pars compacta. Although PD is primarily defined as a motor disorder, prodromal non-motor symptoms - such as circadian clock desynchronization and sleep disturbances - can emerge years before clinical di...