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Open access Oct 2026

Outcomes following biliary decompression interventions for jaundiced patients with malignant intrahepatic obstruction from metastatic cancer.

Despite high technical success, only 38% achieved bilirubin ≤2 mg/dL after IBDI and median survival was 7 weeks, highlighting the importance of careful patient selection and earlier goals-of-care discussions.

Tessa Crilley, Adeel Arshad, Mitchell L. Ramsey et al. · 0 citations
Review Open access Sep 2026

CD38 in hepatic pathobiology: mechanisms, disease association and therapeutic implications.

CD38 is a highly conserved multifunctional enzyme that regulates intracellular calcium signaling and NAD⁺ metabolism. Although extensively studied in cancer and autoimmune diseases, growing evidence points to a critical role for CD38 in both normal and diseased liver physiology. In hepatic tissue, CD38 is expressed on...

J. Eng, Blake R. Peterson, Sylvester M. Black · 0 citations

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