Author

J. Ferreira-Strixino

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Open access Oct 2026

Nanostructured Hybrid Matrix Device: An Engineered Approach for Localized Photodynamic Therapy in 9L/lacZ Cell Models

Gliosarcoma treatment remains a challenge due to its aggressiveness and high recurrence rates. This study describes the development and characterization of a novel hybrid drug delivery system (DDS) for localized photodynamic therapy (PDT). The system consists of a PVA/gelatin hydrogel encapsulated with hydroxyapatite m...

J. A. R. Ambrósio, J. A. Carvalho, Letícia G. M. Pinto et al. · ACS Omega · 0 citations

Open access Oct 2026

Highly Stable PLA/Gelatin Bionanocomposites for Enhanced Delivery of Chloroaluminum Phthalocyanine for Photodynamic Therapy against SK-MEL-28 Cells

This study reports the development of a biodegradable poly(lactic acid) and gelatin (nPLA-G) bionanocomposite as a drug delivery system for chloroaluminum phthalocyanine (ClAlPc) in photodynamic therapy (PDT). Using a hybrid desolvation/emulsification technique, we engineered spherical nanoparticles with an average d...

J. A. Carvalho, J. A. R. Ambrósio, M. Beltrame et al. · ACS Omega · 0 citations

Open access Oct 2026

Surface charge-dependent effects of BSA-curcumin nanoparticles combined with amikacin in antimicrobial photodynamic therapy: A pilot In Vivo study of multidrug-resistant Pseudomonas aeruginosa skin infection

Skin infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa represent a significant therapeutic challenge because of high bacterial virulence and increasing antibiotic resistance. In this context, alternative strategies—such as nanotechnology and photodynamic therapy (PDT)—that can be combined with antib...

Isabelle Ribeiro Brambilla, Eloíse Gwyneth Lopes Oliveira, Mariany Fernandes da Silva Gravito de Carvalho et al. · Lasers in Medical Science · 0 citations