Open access
Aug 2026
Dissecting the Genetic Link Between Insulin Resistance and Coronary Heart Disease: A Multi-Trait GWAS and Proteomic-Metabolomic Mediation Analysis
The results map a proteomic and metabolomic axis linking the genetic component of IR to CHD and highlight HDL lipoprotein-subclass biology as a candidate therapeutic and biomarker space.
R. Dong, J. Fu, B. Zhang et al.
· medRxiv · 0 citations