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Author

J. García-Verdugo

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Open access Sep 2026

Cerebral organoids recapitulate interneuron chain migration in the human cortex

It is shown that human cerebral organoids cultured for over six months recapitulate postnatal interneuron migration, enabling its mechanistic and genetic dissection and mechanistic analysis of previously inaccessible aspects of postnatal human brain development and their contributions to neurodevelopmental disease.

Sakurako Nagumo Wong, M. Noble, M. Fischer et al. · 0 citations
Sep 2026

Hypoxic Preconditioning Prevents the Neonatal Lung Against Hyperoxia-Induced Ferroptosis Through the Nrf2-CBS Axis.

AIMS Hyperoxia-induced oxidative injury contributes to ferroptosis and abnormal lung remodeling in preterm infants receiving oxygen therapy. We previously demonstrated that postnatal hypoxic preconditioning (HP) reduces hyperoxia-induced lung injury in a neonatal mouse model. In the present study, we investigated wheth...

Salvador Pérez, Iván Millán, Elena Cubells et al. · 0 citations
Open access Aug 2026

Intracranial Targeting of Cholesterol Processing Reveals a Therapeutic Vulnerability that Reprograms Glioblastoma and Promotes Antitumor Immunity

These findings establish cholesterol dysregulation–induced metabolic collapse as a promising therapeutic approach for GBM using two FDA-approved drugs: the H1 histamine antagonist clemastine and the retinoid X receptor agonist bexarotene.

Maria J. Ulloa-Navas, Rachel M. Whitehead, Vanessa K. Jones et al. · 0 citations

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