Cardiovascular diseases are the number one killer worldwide. Malfunction of the conduction system, heart valves, the myocardial muscle or the vessels irrigating the tissue have been traditionally addressed with medical devices such as pacemakers, left ventricular assist devices, heart valves and vascular grafts. These...
María Flandes-Iparraguirre, Michael J. Vernon, O. Iglesias-García et al.· Biomaterials Advances· 0 citations
The recapitulation of the physiological cellular composition, 3D structure and mechanics of the human myocardium is key to improving the biofabrication of cardiac tissues. To advance the development of engineered heart patches, with significant potential for human cardiac repair, we assessed the impact of their cellula...
O. Iglesias-García, A. Ullate-Agote, Jian Qin et al.· Materials Today Bio· 0 citations
Abstract Objectives The coexistence of multisystemic involvement in a young adult raises the need to consider rare metabolic and mitochondrial disorders. We report a case of late-onset propionic acidemia (PPA) that may have contributed to unmasking Leber hereditary optic neuropathy (LHON), an extremely infrequent assoc...
I. Solares, E. Alegre, Inmaculada Colina et al.· Advances in Laboratory Medic...· 0 citations
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