Author

J. Ge

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Open access Oct 2026

Histone lactylation-mediated metabolic remodeling in vascular smooth muscle cells aggravates aortic aneurysm and dissection via promoting lactate accumulation

Vascular smooth muscle cells (VSMCs) undergo phenotypic changes during the development of aortic aneurysm and dissection (AAD). Metabolism shifts from oxidative phosphorylation (OXPHOS) to glycolysis. Recent studies suggested glycolysis-associated histone lactylation was involved in the regulation of cardiovascul...

L. Liu, J. Ge, A. Sun · European Heart Journal · 0 citations

Open access Oct 2026

Right ventricular-pulmonary arterial coupling in patients with different etiologies of pulmonary arterial hypertension evaluated by three-dimensional echocardiography

Three-dimensional echocardiography permits comprehensive and accurate evaluation of right ventricular (RV) function, offering a reliable noninvasive method for assessing RV-PA coupling and may serve as valuable noninvasive markers for risk stratification and disease monitoring in PAH without intracardiac shunts.

D. Kong, H. Chen, C. Pan et al. · European Heart Journal · 0 citations

Open access Oct 2026

The association between heart rate variability, epicardial adipose tissue, and clinical outcomes in heart failure patients

Heart failure (HF) is driven by both autonomic nervous system dysfunction and metabolic dysregulation. Reduced heart rate variability (HRV) indicates sympathetic overactivity, while epicardial adipose tissue (EAT) remodeling (increased volume and density) reflects local inflammation. However, the interplay betwee...

Y. Yu, W. Lin, L. Shen et al. · European Heart Journal · 0 citations