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Open access Aug 2026

Clinical validation of an optimised metagenomic nanopore sequencing method for detecting viral respiratory pathogens.

BACKGROUND Clinical metagenomics (CMg) offers high-throughput respiratory pathogen detection with a wider range than targeted, probe-dependent diagnostics. Sequencing cost and the challenges of high host biomass are barriers to the use of CMg in high-throughput respiratory pathogen detection in non-invasive samples suc...

N. Sanderson, K. Dingle, K. Hopkins et al. · 0 citations
Open access Aug 2026

Validation of an optimized Oxford Nanopore sequencing workflow versus Illumina for mycobacteria from primary MGIT culture

ABSTRACT Illumina short-read sequencing of primary Mycobacterial Growth Indicator Tube (MGIT) cultures is an established approach for mycobacterial genomic characterization but relies on labor-intensive workflows and centralized sequencing facilities. Oxford Nanopore Technologies (ONT) offers long-read sequencing and i...

Catriona S Baker, M. Colpus, J. Gentry et al. · 0 citations

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