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J. Giarolla

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Open access Aug 2026

Innovative drug-modified low-generation PAMAM dendrimer complexes for enhancing the solubility and permeability of BCS class II and IV drugs.

The aqueous solubility and membrane permeability of Biopharmaceutics Classification System (BCS) class II and IV drugs, such as furosemide (FUR), sulfadiazine (SDZ), verapamil (VEP), mefloquine (MEF), and the bioactive compound quercetin (QUE), are low. Thus, affecting the oral bioavailability of these drugs. In our st...

Felipe Guizze, S. Sueyoshi, Helena Castilho et al. · 0 citations

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