Open access
Aug 2026
CTCF delimits a DNA methylation transition at the intergenic region between the embryonic and adult α-globin genes
A conserved role of CTCF is supported in preventing DNA methylation spreading and gene silencing of cell-type-specific genes along differentiation, and a similar role of CTCF on DNA methylation and gene expression in the human orthologous gene HBA2.
Gustavo Tapia-Urzúa, H. N. Núñez-Martínez, Sylvia Garza-Manero et al.
· Epigenetics · 0 citations