Background Chronic lung allograft dysfunction (CLAD) is the leading cause of death beyond the first year after lung transplantation, and its most frequent phenotype is bronchiolitis obliterans syndrome (BOS), a fibrotic small-airway disease. Mechanistic work has focused on the immune compartment, yet intensified immuno...
Jannik Ruwisch, Hande Yilmaz, Leonard Christian et al.· bioRxiv· 0 citations
Chronic lung allograft dysfunction (CLAD) is the leading cause of late morbidity and mortality after lung transplantation. Bronchiolitis obliterans syndrome (BOS), a major CLAD phenotype, is characterized by obliterative bronchiolitis (OB). While microvascular perturbations are described in BOS, their cellular and mole...
Axelle Coppens, Rahel Bodenmann, Janik Riese et al.· American Journal of Transpla...· 0 citations
Fibrotic interstitial lung diseases (fILDs) encompass a heterogeneous group of interstitial lung diseases (ILDs) and may arise from persistent inflammation caused by systemic disease or environmental exposures. Idiopathic pulmonary fibrosis (IPF), the prototypical fILD, is characterized by progressive fibrosis, limited...
Nazanin Nazemi, Bruno Crestani, D. Helou et al.· European Respiratory Journal· 0 citations
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