Author

J. Halfvarson

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Open access Oct 2026

Altered MAIT cell activation characteristics with impaired IL-10 and IL-17A response programs in active Crohn’s disease

Abstract Mucosa-associated invariant T (MAIT) cells are innate-like MR1-restricted T cells broadly distributed in human tissues. MAIT cells adapt their antigen-specific response patterns depending on cytokine cues such as IL-12 or IL-18 in the microenvironment, shifting toward either IL-10+ or IL-17+ profiles. However,...

Elli Mouchtaridi, J. Halfvarson, Jeffrey Y. W. Mak et al. · Journal of Immunology · 0 citations

Open access Aug 2026

The Utility of Faecal Biomarkers in the Discrimination Between Acute Gastroenteritis and Inflammatory Bowel Disease

Faecal biomarkers reflecting neutrophil, eosinophil, and epithelial activity may provide complementary information in the differentiation of patients with suspected acute GE and new-onset IBD, suggesting that faecal HNL may have the ability to distinguish between these conditions.

M. Lundström, Christer G. B. Peterson, David Amcoff et al. · Biomedicines · 0 citations

Open access Sep 2026

Impact of Family History on Colorectal Cancer Risk in Inflammatory Bowel Disease and in Matched General Population Comparators.

Family history of CRC increased CRC incidence similarly in IBD and matched comparators, with the greatest increase in individuals with multiple affected relatives, raising the question if surveillance strategies should instead prioritize patients with multiple affected relatives.

Å. H. Everhov, Kári Kristjánsson, J. Ludvigsson et al. · Gastroenterology · 0 citations