Amyloid and tau positivity in DLB were associated with worse global cognitive outcomes, but not with motor performance, and NfL levels were elevated across diseases, and total α‐synuclein levels were associated with tau positivity.
Marianna Rizzo, C. Teunissen, H. Zetterberg et al.· Alzheimer's & Dementia· 0 citations
Introduction Emotion recognition from speech prosody is a complex cognitive ability that depends on the functional integrity of a distributed neuronal network and may be shaped by demographic, clinical and lifestyle factors. The Terrapino mobile application was developed as a tool to promote cognitive health, but its d...
Martin Šimčík, Ross Andel, Jan Pavlík et al.· Frontiers in Psychology· 0 citations
Understanding of the genetic architecture of AD in the context of its main genetic driver is improved, and APOE-stratified insights may help understand and overcome side effects, inform clinical trial enrollment strategies, and create the scientific basis for targeted, mechanism-driven therapies in neurodegenerative di...
J. Thomassen, H. Leonard, Brittany Ulms et al.· Nature Genetics· 0 citations
It is concluded that rare coding CNVs in a proportion of AD-associated genes and 22q11.21 duplication as a strong AD-risk-decreasing factor increase AD risk and Conversely, 22q11.21 duplication as a strong AD-risk-decreasing factor is identified.
O. Quenez, Catherine Schramm, K. Cassinari et al.· American Journal of Human Ge...· 1 citation
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