Author

J. Hyun

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Open access Sep 2026

eNAMPT-IFITM3 axis links neuroinflammation to γ-secretase activation

Summary Amyloid-β (Aβ) accumulation and neuroinflammation are central features of Alzheimer’s disease (AD), yet the molecular link connecting inflammatory signaling to γ-secretase activation remains poorly understood. Here, using a cell-based gain-of-function screen with a cDNA library, we identify nicotinamide phospho...

J. Hyun, Sun-Min Jung, Yoona Noh et al. · iScience · 0 citations

Jul 2026

Comparative Whole-Exome Sequencing of Ambulatory Patients and Transplant Recipients with Idiopathic Dilated Cardiomyopathy.

LMNA variants mark a high-risk transplant-trajectory phenotype in Korean idiopathic DCM, and genetic testing may aid early identification and management of candidates for advanced HF therapies, including HTx and durable MCS.

Ju-Hee Lee, Jinhwa Kong, Seulgi Kim et al. · The Journal of Heart and Lun... · 0 citations