Oct 2026
The IKK complex and TBK1/IKKε are recruited to STING through distinct mechanisms to activate NF-κB signaling.
Stimulator of interferon genes (STING) is a highly conserved signaling molecule that coordinates an antiviral innate immune response through activation of the nuclear factor κB (NF-κB) and interferon regulatory factor 3 (IRF3) signaling pathways. In addition to an antiviral response, STING-mediated NF-κB signaling also...
A. Christensen, Aneta Jurkiewicz, Cathrine Silberbauer Jensen et al.
· Science immunology · 0 citations