J. Jiménez-Borreguero

Polygenic determinants of global atherosclerotic plaque burden and progression assessed by 3D vascular ultrasound in young patients with early coronary artery disease

The rising incidence of early coronary artery disease (eCAD) events, and their recurrence despite medical management, represents a major public health concern, driven by heterogeneous and poorly understood mechanisms. Genetic burden, particularly polygenic risk, is becoming a key determinant of eCAD beyond cardio...