J. L. Pennings

Integrating transcriptomics and molecular AOPs to identify T3-dependent regulation of neuronal development in the human neural progenitor test.

It is demonstrated that absence of T3 inhibits brain development since no T3 condition affects key neurodevelopmental processes in vitro, illustrating the utility of integrating transcriptomics with molecular AOPs to provide a structured, mechanistic framework for evaluating the regulation of neuronal cell proliferatio...