J. Lacirignola

Metagenomic Sequencing for Wastewater-Based Surveillance: Modeling and Experimental Approaches for Determining Limit of Detection

Since the COVID-19 pandemic, wastewater-based surveillance (WBS) has emerged as a key approach to assess community-level health and the evolution of pathogens. To date, most established WBS systems focus on polymerase chain reaction (PCR) based detection and targeted sequencing of known pathogens because these approach...