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J. Lavigne

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Open access Aug 2026

Training a phage to expand its host range: directed evolution against Staphylococcus aureus from diabetic foot infections

ABSTRACT Diabetic foot infections (DFIs) are a major complication of diabetes frequently involving multidrug-resistant Staphylococcus aureus. Their persistence and therapeutic complexity underscore the urgent need for alternatives to conventional antibiotics. Phage therapy offers a promising solution, though its clinic...

Lucile Plumet, Chloé Magnan, M. Morsli et al. · 0 citations
Open access Aug 2026

Circulating blood microbiome biomarkers as liquid biopsy in breast cancer

Circulating tumor material can already be used to help in cancer management, but host–microbiota interactions may add complementary value. This study evaluated a “liquid microbiopsy”, combining cell-free microbial DNA (cf-mbDNA) with host biomarkers of microbial translocation/permeability (LBP, sCD14, I-FABP), to...

W. Jacot, L. Cayrefourcq, C. Dunyach-Rémy et al. · 0 citations
Open access Jul 2026

A secreted AIP-Like peptide from Helcococcus kunzii inhibits the Agr quorum sensing system of Staphylococcus aureus

It is demonstrated that Adh2 suppresses Agr signaling and virulence gene expression while promoting a persistent phenotype, and emerges as a promising candidate for therapeutic modulation of bacterial behavior, particularly in the context of chronic wound infections.

Riham Daher, P. François, R. Vincentelli et al. · 0 citations

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