Open access
Sep 2026
641. Microglial osteopontin is required for myelin structural integrity during brain development
Abstract Background Microglia play essential roles in brain development, including regulation of synaptic pruning, phagocytosis, and myelination. A distinct population of white matter–associated microglia at early postnatal development stage in mouse brain expresses high levels of osteopontin (OPN, Spp1), a multifuncti...
G. Nilsson, C. Zhu, J. Leavenworth et al.
· International Journal of Neu... · 0 citations