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J. Liu

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Open access Oct 2026

Mechanosensitive HEG1-NOTCH1 signals governs endothelial cell function in the pathogenesis of pulmonary hypertension

Endothelial cells (ECs) adapted mechanosensitivity to flow shear-stress are critical for vascular homeostasis. HEG1 as an endothelial mechanosensitive gene exerts anti-hypertensive and atheroprotective effects, yet its regulation of pulmonary endothelial function for pulmonary hypertension (PH) pathogenesis and t...

L. Hu, J. Xu, Y. Ji et al. · 0 citations

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