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Open access Sep 2026

PS13-13. Mammary Gland Metabolomics Due To Feeding Rumen-Protected Methionine During A Heat Stress Challenge in Lactating Holstein Cows.

Heat stress (HS) can damage epithelial tissue, compromising absorption and nutrient uptake, and reducing production performance. We investigated the effects of rumen-protected Met (RPM, Mepron®, Evonik Operations GmbH) prior to and during a HS challenge using electric heat blankets (EHB) on mammary tissue metabolomic...

Danielle de Cássia Martins da Fonseca, Fu-Hou Li, V. Palombo et al. · 0 citations
Open access Sep 2026

Gestational stage alters insulin and mTOR signaling in bovine maternal placentome and fetal liver.

Understanding stage-specific regulation of placental and fetal metabolic signaling pathways is essential to elucidate mechanisms supporting fetal growth and developmental programming in dairy cattle. This study evaluated differences in protein abundance between mid-gestation and late-gestation in placentome and fetal l...

A. Aboragah, Nithat Wichasit, D. N. Sherlock et al. · 0 citations
Aug 2026

Lycopene Alleviates Fatty Acid-Induced Oxidative Stress and Apoptosis in Bovine Mammary Epithelial Cells via the TFEB-Mediated Autophagy Signaling Pathway.

High concentrations of free fatty acids (FFA) during early lactation cause metabolic stress and oxidative damage in bovine mammary epithelial cells. This study explored the protective mechanism of lycopene (LYC), a natural antioxidant, against FFA-induced injury in the MAC-T cells. We found that 1.2 mM FFA induced oxid...

Xin-Yuan Sun, Hongdou Jia, Yuan-Yuan Chen et al. · 0 citations

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