Author

J. Luque‐Garcia

2 papers indexed here

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Open access Jul 2026

Systems-Level Multi-Omics Analysis Resolves the Mechanism of Action of a Novel Multifunctional Nanosystem Against Triple-Negative Breast Cancer

Background/Objectives: Triple-negative breast cancer remains a major therapeutic challenge due to its aggressive behavior and limited treatment options. Methods: In this study, an integrated multi-omics strategy combining SILAC-based quantitative proteomics, shotgun lipidomics, and targeted metabolomics was applied to...

M. P. Buendia-Nacarino, Dominik Bulfon, Nikola Tom et al. · Pharmaceutics · 1 citation

Open access Aug 2026

Therapeutic transformation of a rhodium nanophotosensitizer into a tamoxifen-loaded targeted nano-drug for dual chemo-photodynamic therapy of ER-positive breast cancer.

Rhodium-based nanophotosensitizers have recently emerged as promising platforms for near-infrared (NIR)-activated photodynamic therapy (PDT). However, their therapeutic potential remains largely restricted to reactive oxygen species-mediated cytotoxicity, limiting their ability to address the complex molecular drivers...

Andres Machuca, Alejandro García García, Estefanía García-Calvo et al. · Colloids and Surfaces B: Bio... · 0 citations