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Author

J. Mendiola

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Open access Sep 2026

Plasma and cerebrospinal fluid proteomics reveal distinct patterns of senescence and neuropathology in aging rhesus macaques.

Aging is the primary risk factor for neurodegenerative disease, yet the protein signatures that distinguish physiological brain aging from pathological decline remain incompletely defined in translational models. Using the targeted NULISAseq proteomic platform, we profiled cerebrospinal fluid (CSF) and plasma from 66 r...

Giovanne B. Diniz, Kayla Schwartz, Carissa T. Erices et al. · 0 citations
Open access Aug 2026

Alzheimers disease blood biomarkers reveal proteomic modules of disease progression

Routine and accessible plasma measures can be leveraged to recover reproducible, biologically distinct progression modules that improve characterization of heterogeneous AD and have practical value for risk stratification, trial enrichment, or treatment monitoring.

R. R. Butler, M. Brown, A. Weber et al. · 1 citation

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