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Open access Oct 2026

Single-cell landscape of human adipose tissue reveals THBS1 as a potential driver of fibro-inflammation in metabolic disease

The cellular complexity of adipose tissue plays a critical role in the pathogenesis of metabolic disease; however, mechanisms underlying adipose dysfunction remain poorly understood. Here, we constructed a single-nucleus and bulk transcriptomic atlas of human visceral adipose tissues from an ethnically homogeneous coho...

J. Jung, Eun Seo Park, Nawon Lee et al. · 0 citations
Open access Oct 2026

Prediabetes subtype-based stratification reveals distinct long-term risks for type 2 diabetes.

AIMS/HYPOTHESIS Prediabetes is heterogeneous, with subtypes defined by impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or HbA1c, each with different risks of progression to type 2 diabetes. We compared progression across these subtypes, and evaluated the benefit of adding insulin secretion and sensitiv...

Hun-Jee Choe, Wonsuk Choi, Howard H. Chang et al. · 0 citations

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