Author

J. Neyts

2 papers indexed here

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Open access Sep 2026

Antiviral sugar baits to reduce arbovirus transmission: a proof-of-concept study

Dengue virus (DENV) and chikungunya virus (CHIKV) remain major global health threats, yet approved antiviral therapies are lacking. Antiviral sugar baits (AVSBs) represent a novel transmission-blocking strategy that exploits the natural sugar-feeding behaviour of mosquitoes to deliver antiviral compounds directly to th...

Maeva Van Langendonck, A. Rosales-Rosas, Shannan-Leigh Macleod et al. · bioRxiv · 0 citations

Open access Jul 2026

The 5′-Isobutyryl Ester Prodrug of 4′-Thiouridine Inhibits SARS-CoV‑2 Replication in Culture and in a Syrian Hamster Infection Model

Although the SARS-CoV-2 pandemic is now largely controlled through widespread vaccination and available therapeutics, emerging variants could undermine their overall effectiveness. 4′-Thiouridine (TU) and its 5′-isobutyryl prodrug (iBu TU) were identified as potent inhibitors of SARS-CoV-2 replication across various ce...

Zhe Chen, F. Amblard, M. Kasthuri et al. · ACS Omega · 0 citations