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J. Ong

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#small language model Meta-analysis Open access Oct 2026

Reporting completeness of clinical trials evaluating large language model interventions in medicine: systematic review

Clinical trials of LLM interventions show modest adherence to established reporting guidelines, with persistent underreporting of LLM specific methodological details, reproducibility artefacts, and harms reporting required to support reproducibility and confident appraisal of safety risks before their clinical translat...

David Chen, A. Blayne, T. Ning et al. · 0 citations
Review Open access Aug 2026

Evaluating large language model performance in US FDA regulatory science

This study compares the performance of three LLMs in extracting, analyzing, and synthesizing regulatory and clinical information from FDA drug reviews, guidance for the industry, and drug labels as accessed through their standard user interfaces, using antibiotics approved for complicated urinary tract infections betwe...

Khulud Bukhari, R. Rodriguez-Monguio, B. Lopez-Bermudez et al. · 0 citations

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