Open access
Aug 2026
Direct Observation of Structural Unraveling in PABPN1 Polyalanine Expansions
The data help to define key mechanistic features in pathogenic misfunction induced by homorepeat expansions and identify specific structural motifs as potential targets for fragment-based binders to restore protein functionality in polyalanine expansion disorders.
Rosa Antón, J. Oroz
· ACS Bio & Med Chem Au · 0 citations