OBJECTIVES
Group A Streptococcus (GAS) is a leading global cause of infectious disease morbidity and mortality. A major barrier to GAS vaccine development is our incomplete understanding of human immunity. We undertook, to our knowledge, the first systematic review describing human antibody responses following GAS infe...
Rachael Barr, Hannah Frost, Yara-Natalie Abo et al.· Journal of Infection· 0 citations
Streptococcus pyogenes (group A Streptococcus; Strep A) causes a broad spectrum of diseases ranging from pharyngitis and skin infections to invasive disease and immune-mediated complications including acute rheumatic fever (ARF) and rheumatic heart disease (RHD). RHD remains one of the most important causes of cardiova...
Kimberly S. Davis, K. Le Doaré, J. Vekemans et al.· Vaccine· 0 citations
Streptococcus pyogenes (Group A Streptococcus, GAS) is among the leading causes of infectious mortality and primarily manifests as acute pharyngitis. The development of an effective vaccine continues to be hindered by an incomplete understanding of the host immune response, particularly in the oropharynx. Here, we prov...
Anuk D. Indraratna, D. Cox, P. Das et al.· bioRxiv· 0 citations
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