Local Suppression of Dgat2 Augments Fatty Acid Oxidation in Skeletal Muscle in High-Fat Diet-Fed Mice
Diacylglycerol acyltransferase 2 (DGAT2) codes an enzyme which synthesize triglyceride by esterifying fatty acid to last portion of diacylglycerol backbone, and contributes to intramyocellular lipid metabolism. Small interfering RNA (siRNA)-mediated knockdown of Dgat2 was previously shown to reduce AKT phosphorylation...