Author

J. Pérez-Urizar

2 papers indexed here

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Open access Sep 2026

Bioequivalence Assessment of Sitagliptin/Metformin Extended-Release Fixed-Dose Combinations in Healthy Mexican Subjects Under Fasting and Fed Conditions

Background/Objectives: Management of Type 2 Diabetes (T2D) frequently requires combination therapy. Fixed-dose combinations (FDCs) of sitagliptin and extended-release (ER) metformin improve therapeutic adherence but pose biopharmaceutical challenges related to matrix robustness and food–drug interactions. This study ev...

Omar Emmanuel Hernández Piña, Porfirio de la Cruz-Cruz, Erika Gabriela Guido Ávila et al. · Pharmaceuticals · 0 citations

Open access Aug 2026

Etoricoxib–Betamethasone Combination Attenuates Inflammatory Nociception and Edema in Adjuvant-Induced Arthritis via Cytokine and Macrophage Axis Modulation

Background/Objectives: Acute inflammatory episodes demand rapid symptom control while limiting systemic exposure. We assessed whether co-therapy with the selective cyclooxygenase-2 (COX-2) inhibitor etoricoxib and the corticosteroid betamethasone provides antinociceptive and anti-edema activity in a rat model with comp...

J. Pérez-Urizar, I. Torres-Roque, V. Rangel-Ramírez et al. · Pharmaceuticals · 0 citations