Structural biology is moving beyond the determination of static molecular structures toward quantitative descriptions of biomolecular mechanisms. Modern questions increasingly focus on conformational heterogeneity, exchange kinetics, weak and transient interactions, allostery, disorder, assembly, and phase behavior. Th...
J. Purslow, Vincenzo Venditti· Frontiers in Molecular Biosc...· 0 citations
The backbone 1H, 15N, 13C chemical shift assignment of E. coli AlkB in complex with Zn2+ and α-ketoglutarate is reported, allowing investigations of the protein structural dynamics anticipated to provide crucial insight regarding fundamental aspects in the recognition and enzyme regulation processes.
Sayan Das, J. Purslow, Kyle Malcom et al.· Biomolecular NMR Assignments· 0 citations
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