Open access
Jul 2026
Selective GPR17 antagonism enhances structural and functional recovery in animal models of demyelination
Oral treatment results in robust functional recovery consistent with remyelination, as evidenced by improved spatial memory and recovery of visual evoked potential latency delays, and highlights this G protein-coupled receptor as a promising therapeutic target for demyelinating disorders.
Dille De Herdt, E. Lefevere, Véronique Brouwers et al.
· PLoS ONE · 0 citations