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J. R. Espinosa

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#graph neural networks Review Open access Sep 2026

Antibody-drug conjugate engineering: from design to efficacy and safety

Antibody–drug conjugates (ADCs) represent a rapidly expanding class of targeted cancer therapeutics that combine the high selectivity of monoclonal antibodies with the potent cytotoxic activity of small-molecule drugs. Their clinical success relies on the simultaneous optimization of multiple interdependent parameters,...

Alberto Ocaña, J. R. Espinosa, C. Alonso-Moreno et al. · 0 citations

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