FOXM1, a forkhead-box transcription factor, is consistently overexpressed in breast cancer, particularly in the basal-like and triple-negative subtypes, in which high expression predicts poor survival. We propose, as a falsifiable hypothesis rather than an established mechanism, that FOXM1 may function as a dosage-inte...
G. Oriquat, Hani Moslem Ahmed, J. Rizaev et al.· Frontiers in Oncology· 0 citations
Cancer remains a leading cause of morbidity and mortality worldwide, demanding innovative strategies for diagnosis, therapy, and immune modulation. Advances in nanomedicine have positioned MXene quantum dots (MQDs) as promising multifunctional platforms for cancer theranostics due to their tunable physicochemical pro...
T. Alramadneh, J. Rizaev, Jakhongir Norqulov et al.· Surface and Interface Analys...· 0 citations
Congenital hydronephrosis caused by ureteropelvic junction obstruction (UPJO) remains one of the main causes of chronic kidney disease in childhood. Laparoscopic pyeloplasty has become the standard of treatment; however, in young children its performance is associated with technical difficulties. In addition, tradition...
I. Akhmedov, S. P. Yatsyk, J. Rizaev et al.· PEDIATRIA Journal named afte...· 0 citations
The development of tuberculosis (TB) is dictated by a complicated interplay between antimicrobial defense and host‐mediated immunopathology. Neutrophils are known to exhibit striking functional plasticity with phenotypes associated with both bacterial containment and tissue damage. However, the mechanisms that connect...
K. Hamdan, J. Rizaev, Dhara N. Patel et al.· Cell Biology International· 0 citations
The transcriptional coactivators p300 and CREB-binding protein (CBP) integrate chromatin remodeling, enhancer activity, lysine acetylation, immune signaling, and tumor-suppressor control, making them recurrent targets of viral proteins. This narrative review examines p300/CBP at the virus-cancer interface, prioritizing...
A. Atoom, J. Rizaev, D. Polatova et al.· Cancer Treatment and Researc...· 0 citations
Oncolytic virotherapy has evolved from a tumor-selective cytolytic strategy into a programmable immunotherapeutic platform that reshapes the tumor microenvironment (TME). Oncolytic viruses (OVs) selectively infect malignant cells, induce immunogenic cell death, release tumor antigens, and activate innate and adaptive i...
A. Atoom, J. Rizaev, D. Polatova et al.· Cancer Treatment and Researc...· 0 citations
The regulatory mechanisms linking ferroptosis and the tumor immune microenvironment are highlighted, a critical discussion of recent developments in bionanomaterial‐based therapeutic platforms is provided, and the challenges and prospects for clinical application of these platforms for immunotherapy are outlined.
Usamah Sayed, J. Rizaev, R. Turaev et al.· Journal of Cellular Biochemi...· 0 citations
This review integrates current knowledge of circRNA biogenesis and molecular function, surveys cancer-type-specific circRNA expression signatures, and evaluates evidence for their utility in MRD monitoring across hematologic and solid malignancies, and proposes multilayered diagnostic frameworks combining circRNA profi...
T. Alramadneh, Hussein Salim Abed, Sarah Qutayba Badraldin Qutayba Badraldin et al.· Journal of Investigative Med...· 0 citations
A comprehensive assessment of advancements and challenges in PSCs, MSCs, RPCs, and RPE, a methodical examination of the disparity between structural engraftment and genuine functional integration, and a cohesive discourse on innovative strategies such as optogenetics, 3D bioprinting, and extracellular vesicle-based the...
B. Jaber, M. Abd, S. Younis et al.· International Immunopharmaco...· 0 citations
This review argues that circular topology should be viewed as an active pharmacologic variable, not merely a stability enhancement, and dissect recent advances in cap-independent translation initiation, including IRES elements and m6A-driven mechanisms, rolling-circle translation for multi-epitope vaccine design, and p...
Amr A. El-Sehrawy, H. Al-Ameer, J. Rizaev et al.· Biotechnology and Bioenginee...· 0 citations
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