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This work presents Semi-supervised Omics Factor Analysis (SOFA), a method that incorporates known covariates into the model upfront and focuses the factor discovery on novel sources of variation.
EMBL AI Librarian is introduced, a knowledge layer that upgrades the Europe PMC interface for AI agents that improves performance across a range of tasks: literature synthesis, claim verification, open-domain question answering, and downstream biology tasks such as protocol questions and sequence manipulation.
An integrated whole-genome and transcriptome workflow is developed to systematically distinguish functionally credible, predictive driver aberrations from non-functional alterations across all classes of genomic events in ovarian high-grade serous carcinoma.
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