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Author

J. Sandberg

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Open access Oct 2026

Altered MAIT cell activation characteristics with impaired IL-10 and IL-17A response programs in active Crohn’s disease

Abstract Mucosa-associated invariant T (MAIT) cells are innate-like MR1-restricted T cells broadly distributed in human tissues. MAIT cells adapt their antigen-specific response patterns depending on cytokine cues such as IL-12 or IL-18 in the microenvironment, shifting toward either IL-10+ or IL-17+ profiles. However,...

Elli Mouchtaridi, J. Halfvarson, Jeffrey Y. W. Mak et al. · 0 citations
Open access Sep 2026

MAIT cell responses to Staphylococcus aureus and sensitivity to HlgAB toxin are modulated by activation and tissue-dependent virulence effects

ABSTRACT Mucosa-associated invariant T (MAIT) cells are unconventional T cells with innate-like rapid antimicrobial effector functions and serve as resident sentinels at mucosal and non-mucosal barriers. However, their role in immune defense against Staphylococcus aureus and the impact of bacterial immune evasion mecha...

Elisa J. M. Raineri, Caroline Boulouis, Elli Mouchtaridi et al. · 0 citations

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