Author

J. Schatz

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Open access Oct 2026

Chromatin-informed cell-free DNA approach for detection of clinically measurable disease in multiple myeloma.

Multiple myeloma (MM) is monitored using bone marrow-based minimal residual disease (MRD) assays, which provide high sensitivity but require repeated invasive sampling and are limited to a single anatomical site. Cell-free DNA (cfDNA) offers a minimally invasive alternative, yet most cfDNA approaches rely on prior tumo...

Palak Bajaj, D. Abelman, P. Luo et al. · Blood Advances · 0 citations

Open access Sep 2026

RHOA Deletion Downregulates CD19 and Promotes Dysfunctional Immune Microenvironments in CAR-T Resistant Large B-cell Lymphomas

CD19-directed chimeric antigen receptor (CAR)-T cells are breakthrough therapies for large B-cell lymphomas, but fewer than half of patients achieve durable responses. We previously showed RHOA deletions are enriched in progressing cases, but the role of RHOA deficiency is poorly defined despite frequent occurrence in...

A. Newsam, B. Ziccheddu, A. Youssfi et al. · Blood Cancer Discovery · 0 citations